Williams+Syndrome

Wliams syndrome is known by many names; Beuren syndrome, Elfin Facies syndrome, Elfin Facies with Hypercalcemia, Hypercalcemia- Supravalvar Aortic Stenosis, Infantile Hypercalcemia, Supravalvar Aortic Stenosis Syndrome, WBS, Williams Beuren Syndrome, WMS, WS. Williams Syndrome only affects an estimated 1 in 7, 500 to 20,000 people. The genes that are involved is the deletion of genetic material from a specific region of chromosome 7; and CLIP2, ELN, GTF2IRDI, and LIMK1 are genes that are typically deleted in people with William’s Syndrome. The chromosome that those genes are located on is Chromosome 7. Most cases are not inherited, and only occur as random events during formation of reproductive cells (eggs or sperm) in the parent of an affected individual. Cases occur in people with no history of the disorder in their families’ history. Williams’s syndrome is a developmental disorder that affects many parts of the body. It is mainly characterized by mild to moderate intellectual disability or learning problems, unique personality, characteristics, distinctive facial features, and heart and blood vessel (cardiovascular) problems. People have difficulty with visual-spatial tasks such as drawing and assembling puzzles. Victims tend to do well on tasks that involve spoken language, music, and learning by repetition (role memorization). Affected people have outgoing and engaging personalities and tend to take an extreme interest in other people. Attention Deficit disorder (ADD) problems with anxiety and phobias are common among people with the disease. Children have distinctive facial features including broad forehead, short nose with broad tip, full cheeks and wide mouth with full lips. Many people have dental problems such as small, widely, spaced teeth that are crooked or missing. Older children and adults, the face appears longer and more gaunt. Supravalvar aortic stenosis (SVAS) occurs frequently in people with Williams Syndrome. There is currently no cure or treatment for Williams Syndrome. For people with Williams Syndrome, avoid taking extra calcium and Vitamin D. Treat high levels of blood calcium if present. Blood vessel narrowing can be a significant health problem and is treated based on its severity. Physical therapy is helpful to patients with joint stiffness. Developmental and speech therapy can help children (verbal strengths can make up for other weaknesses). Other treatments are based on patients’ symptoms. Williams Syndrome is currently gaining wider popularity in research field due to its unique characteristics and wealth of information it is providing to the human Genome Research Projects concerning Williams Syndrome specify in Chromosome 7 generically fluctuate rapidly. Because of the fluctuation, it is impossible to p Williams syndrome is known by many names; Beuren syndrome, Elfin Facies syndrome, Elfin Facies with Hypercalcemia, Hypercalcemia- Supravalvar Aortic Stenosis, Infantile Hypercalcemia, Supravalvar Aortic Stenosis Syndrome, WBS, Williams Beuren Syndrome, WMS, WS. Williams Syndrome only affects an estimated 1 in 7, 500 to 20,000 people. The genes that are involved is the deletion of genetic material from a specific region of chromosome 7; and CLIP2, ELN, GTF2IRDI, and LIMK1 are genes that are typically deleted in people with William’s Syndrome. The chromosome that those genes are located on is Chromosome 7. Most cases are not inherited, and only occur as random events during formation of reproductive cells (eggs or sperm) in the parent of an affected individual. Cases occur in people with no history of the disorder in their families’ history. Williams’s syndrome is a developmental disorder that affects many parts of the body. It is mainly characterized by mild to moderate intellectual disability or learning problems, unique personality, characteristics, distinctive facial features, and heart and blood vessel (cardiovascular) problems. People have difficulty with visual-spatial tasks such as drawing and assembling puzzles. Victims tend to do well on tasks that involve spoken language, music, and learning by repetition (role memorization). Affected people have outgoing and engaging personalities and tend to take an extreme interest in other people. Attention Deficit disorder (ADD) problems with anxiety and phobias are common among people with the disease. Children have distinctive facial features including broad forehead, short nose with broad tip, full cheeks and wide mouth with full lips. Many people have dental problems such as small, widely, spaced teeth that are crooked or missing. Older children and adults, the face appears longer and more gaunt. Supravalvar aortic stenosis (SVAS) occurs frequently in people with Williams Syndrome. There is currently no cure or treatment for Williams Syndrome. For people with Williams Syndrome, avoid taking extra calcium and Vitamin D. Treat high levels of blood calcium if present. Blood vessel narrowing can be a significant health problem and is treated based on its severity. Physical therapy is helpful to patients with joint stiffness. Developmental and speech therapy can help children (verbal strengths can make up for other weaknesses). Other treatments are based on patients’ symptoms. Williams Syndrome is currently gaining wider popularity in research field due to its unique characteristics and wealth of information it is providing to the human Genome Research Projects concerning Williams Syndrome specify in Chromosome 7 generically fluctuate rapidly. Because of the fluctuation, it is impossible to provide an exact list of active research projects. Many research centers specialize in the area of Williams Syndrome.
 * Williams Syndrome **

Williams syndrome is known by many names; Beuren syndrome, Elfin Facies syndrome, Elfin Facies with Hypercalcemia, Hypercalcemia- Supravalvar Aortic Stenosis, Infantile Hypercalcemia, Supravalvar Aortic Stenosis Syndrome, WBS, Williams Beuren Syndrome, WMS, WS. Williams Syndrome only affects an estimated 1 in 7, 500 to 20,000 people. The genes that are involved is the deletion of genetic material from a specific region of chromosome 7; and CLIP2, ELN, GTF2IRDI, and LIMK1 are genes that are typically deleted in people with William’s Syndrome. The chromosome that those genes are located on is Chromosome 7. Most cases are not inherited, and only occur as random events during formation of reproductive cells (eggs or sperm) in the parent of an affected individual. Cases occur in people with no history of the disorder in their families’ history. Williams’s syndrome is a developmental disorder that affects many parts of the body. It is mainly characterized by mild to moderate intellectual disability or learning problems, unique personality, characteristics, distinctive facial features, and heart and blood vessel (cardiovascular) problems. People have difficulty with visual-spatial tasks such as drawing and assembling puzzles. Victims tend to do well on tasks that involve spoken language, music, and learning by repetition (role memorization). Affected people have outgoing and engaging personalities and tend to take an extreme interest in other people. Attention Deficit disorder (ADD) problems with anxiety and phobias are common among people with the disease. Children have distinctive facial features including broad forehead, short nose with broad tip, full cheeks and wide mouth with full lips. Many people have dental problems such as small, widely, spaced teeth that are crooked or missing. Older children and adults, the face appears longer and more gaunt. Supravalvar aortic stenosis (SVAS) occurs frequently in people with Williams Syndrome. There is currently no cure or treatment for Williams Syndrome. For people with Williams Syndrome, avoid taking extra calcium and Vitamin D. Treat high levels of blood calcium if present. Blood vessel narrowing can be a significant health problem and is treated based on its severity. Physical therapy is helpful to patients with joint stiffness. Developmental and speech therapy can help children (verbal strengths can make up for other weaknesses). Other treatments are based on patients’ symptoms. Williams Syndrome is currently gaining wider popularity in research field due to its unique characteristics and wealth of information it is providing to the human Genome Research Projects concerning Williams Syndrome specify in Chromosome 7 generically fluctuate rapidly. Because of the fluctuation, it is impossible to provide an exact list of active research projects. Many research centers specialize in the area of Williams Syndrome.

List of Foundations; Williams Syndrome Association, Williams Syndrome Foundation, Williams Syndrome Foundation (United Kingdom), Williams Syndrome Support Group of Victoria, Bundes verband William-Beuren Syndrome, Asociacion Argentina de Sindrome de Williams, Buenos Aires, Williams Syndrome Association Of Belgium, Canadian Association for Williams Syndrome (CAWS), Williams-France EST, Le Syndrome de Williams de Beuren (S.W.B.) Nord Dos-de-Calais, Association de syndrome de Williams et Beuren de France, Magyar Williams Sidroma Tarsasag, Williams syndrome Association of Ireland, Williams Syndrome Of Israel, Associazion Italia Sindrome di Williams ASW(Italy), Williams Syndrome Association of New Zealand, Norsk Forening for US Norway, Asociacion Sindrome de Williams (Spain) A.S.W. (Espana), Asociacion Valencia Sindrome de Williams, Williams Syndrome of Sweden.

Interesting information on Williams Syndrome; inward bend of the small finger (clinodactyly), personality traits including being very friendly: trusting strangers: fearing loud sounds or physical contact: and being interested in music