Duchenne+Muscular+Dystrophy

**[[image:dwe00212g01.gif width="272" height="369" align="right"]]Duchenne Muscular Dystroph**y
__ Is the disease known by any other names? __   ·   Becker ·  DBMD ·  DMD ·  Muscular Dystrophy ·  Steinert’s Disease · __ How common is this disease? __   ·   It occurs in about every 3,600 male infants and this disease only occurs in males. __ What gene(s) are involved? __ ·  X-chromosomes, DMD gene __ What chromosome is that gene on? __ ·  It is on the X-Chromosome __ How do people inherit this disorder? Be sure to list any groups of people that is more common in. __ ·  It is inherited by incorrect or missed genetic information that prevents the body from making the proteins needed to build and maintain healthy muscles in order to function properly. ·  It is most common in males between the ages of 3-12

__ List the symptoms of the disorder. Be sure to tell at what age the symptoms usually appear. __ ·  It begins in the legs and pelvis. Severe case starts in the legs, pelvis, arms, neck and other areas in the body. ·  Frequent falls ·  Rapidly worsening in weakness ·  Difficulty with motor skills __ What kind of medicine and treatment are there to deal with this disorder? __ · __ Gene Therapy __ - genes are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it’s the proteins that perform most life functions and even make up the majority of cellular structures. When genes are altered so that the encoded proteins are unable to carry out their normal functions, genetic disorders can result. __ Discuss the current research on the topic __ ? ·  What they are doing now is phase 1 clinical study of BMN 195. ·  More people are funding scientists for this disease that more testing is getting done. __ List any foundation that exists to raise money for this disease. What is the main goal of the foundation? __ ·  Parent Project Muscular Dystrophy ·  Parents help in an effort to reduce the times of diagnoses. __ List any other interesting information you found about your topic. __ ·  It effect nearly 110,000 people in the world ·  It is a long term affect if your case in to the extreme. __ Find and summarize an article about a personal story about this disease. List the name of the article. __ Jesse’s Journey That's the question that led to the birth of // Jesse's Journey // when one family dared to dream about what's possible after learning the crushing news that Duchene muscular dystrophy had become a part of their daily lives. When John and Sherene Davidson learned that their middle son Jesse was diagnosed with Duchene they charted a life changing course for themselves-setting out to raise research funds to find the elusive cure. The story of Jesse's Journey began to unfold in the summer of 1995 when John Davidson- at the age of 49-set out on an incredible mission to push his 15 year old son Jesse across Ontario in his wheelchair-a trek of 3339 kilometers. The journey became a rallying point for people in communities across Ontario and across Canada. This grueling test of endurance for a determined father and son generated $1.5 million dollars for research. Three years later there was another chapter in the amazing story. In 1998 John Davidson found himself on the road again-this time alone. On his son Jesse's 18th birthday John dipped his running shoes in the Atlantic Ocean at St. John's Newfoundland. 286 days later he dipped those same running shoes in the Pacific at Beacon Hill Park in Victoria. The 8300 kilometer journey across Canada generated $2 million dollars in grassroots donations made by Canadians coast to coast. From their humble beginning the Davidson's managed to bring the [|Jesse] [|Davidson Endowment] on stream. The means was at hand to begin funding research each and every year. In 2000-2001 John Davidson wrote A Canadian Story. This book was written from journals kept during both walks. The story makes a bold statement. It is an inspiring and captivating story about how an ordinary man and his son accomplished something extraordinary. On every page you will feel the heart of Canada and its people.
 * __ Physical Therapy __ - Physical therapists supervise active exercise, passive stretching, hydro-based (water) therapy, as well as regularly monitoring the spine, musculoskeletal, and respiratory function.